From the East Bay, take the 9th Street/Civic Center exit. This turns into Harrison Street. Stay on Harrison until 16th Street, and turn left. Go six blocks to San Bruno Avenue and turn left to reach the Main gallery; to reach the West gallery, turn left one block earlier, at Utah Street.

From the South Bay, take 101 north to the Vermont Street exit. Turn left on Vermont, and drive two blocks to 16th Street. Turn right on 16th, go one block, and turn left on Kansas Street (which turns into Henry Adams Street) travel one block to reach Ed Hardy San Francisco just beyond the corner FifteenthStreet and Henry Adams.

From Marin County and the North Bay, take the Golden Gate Bridge to Lombard Street. Turn right from Lombard to Van Ness Avenue. Stay on Van Ness, crossing Market Street, where Van Ness becomes South Van Ness. Stay on South Van Ness for eight blocks. Turn left onto 16th Street and continue eleven more blocks. Turn left onto Kansas Street (which turns into Henry Adams Street) travel one block to Fifteenth Street to reach Ed Hardy San Francisco which is just beyond the corner of Fifteenth and Henry Adams Streets.